Selected publications:
Ciuba K.#, Piotrowska A.#, Chaudhury D., Dehingia B., Duński E., Behr R., Soroczyńska K., Czystowska-Kuźmicz M., Abbas M., Figiel I., Włodarczyk J., Verkhratsky A, Niedbała M., Kaspera W., Wilczyński B., Pękowska A.^ Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to brain evolution. bioRxiv 2023.12.12.570426; doi: https://doi.org/10.1101/2023.12.12.570426 (Under review)
Verkhratsky A.^, Arranz AM, Ciuba K., Pękowska A.^ Evolution of neuroglia. Annals of the New York Academy of Sciences (2022), https://doi.org/10.1111/nyas.14917
Dehingia B., Milewska M., Janowski M. & Pękowska A. CTCF shapes chromatin structure and gene expression in health and disease. EMBO Reports (2022), e55146; https://doi.org/10.15252/embr.202255146.
Janowski M., Milewska M., Zare P., & Pękowska A., Chromatin Alterations in Neurological Disorders and Strategies of (Epi) Genome Rescue. Pharmaceuticals 2021, 14(8), 765.
Pękowska A.^, Klaus B, Xiang W., Severino J., Daigle N., Klein F.A., Oleś M., Casellas R., Ellenberg J., Steinmetz L.M.S., Bertone P.^, Huber W.^ Gain of CTCF-anchored chromatin loops marks the exit from naive pluripotency. Cell Systems Nov. 28; 7(5):482-495.
Vian L.#, Pękowska A.#, Rao SSR.#, Kieffer-Kwon K-R#, Jung S#, Baranello L., Huang SC., El Khattabi L., Dose M., Pruett N., Sanborn AL., Canela A., Maman Y., Oksanen A., Resch W., Li X., Lee B., Kovalchuk AL., Tang Z., Nelson S., Di Pierro M., Cheng RR., Machol I., St Hilaire BG., Durand NC., Shamim MS., Stamenova EK., Onuchic JN., Ruan Y., Nussenzweig A., Levens D., Aidn EL., Casellas R. The energetics and physiological impact of cohesin extrusion. Cell 2018 May 17;173(5):1165-1178.e20.
Schwarzer W.#, Abdennur N.#, Goloborodko A.#, Pękowska A., Fudenberg G., Loe-Mie Y., Fonseca N.A., Huber W, Haering C., Mirny L., Spitz F. Two independent modes of chromosome organization are revealed by cohesin removal. Nature 2017 Nov 2;551(7678):51-56
Pękowska A.#, Benoukraf T.#, Zacarias-Cabeza J.#, Belhocine M., Koch F., Holota H., Imbert J. Andrau JC., Ferrier P., Spicuglia S. H3K4 tri-methylation provides an epigenetic signature of active enhancers. EMBO J. 2011;(July):1–13.
Pękowska A., Benoukraf T., Ferrier P., Spicuglia S. A unique H3K4me2 profile marks tissue-specific gene regulation. Genome Research, 2010 Nov; 20(11):1493–502.
# equal contribution ^ corresponding author